Which of the following is a symptom associated with tularemia?

The choice indicating high fever is associated with tularemia because this disease, caused by the bacterium Francisella tularensis, typically presents with a range of acute symptoms, the most prominent of which is a sudden high fever. This fever usually develops rapidly and is often accompanied by chills, malaise, and other systemic symptoms.

Tularemia can manifest in different forms depending on how the infection is acquired, but the fever is a common symptom across these various presentations. In cases such as the ulceroglandular form, patients may also experience swollen lymph nodes, which is often accompanied by the high fever. Therefore, recognizing high fever as a key symptom can help in early diagnosis and treatment of the condition.

The other symptoms such as chronic fatigue, joint pain, and severe headaches can be associated with various illnesses but are not primary symptoms of tularemia specifically. While tularemia can potentially cause fatigue and malaise due to the body's immune response, the hallmark of the disease remains the acute onset of fever.